Our Technology
Using state-of-the-art technology, Antibody Analytics has been able to take their Bioanalysis capabilities even further
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See some of the ways that we can help
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Biacore 8K
Antibody Analytics utilises the incredible Biacore 8K system to perform protein interaction analysis. It is widely accepted that SPR as a technology enables efficient screening, characterisation, process optimisation and quality control of biotherapeutics.
As a high throughput and highly sensitive system, Biacore 8K technology allows us to provide our customers with a single solution for large- and small-scale binding analysis e.g. Epitope binning, ranking, kinetics, affinity and everything in between.
XCELLIGENCE RTCA MP
Being able to apply real time cell analysis to our cytotoxicity platforms has unlocked valuable data for our customers at various stages of drug development. Unlike traditional assay endpoints, xCELLigence allows cells to be monitored, in the absence of labels, continuously and automatically throughout the entire course of an experiment.
At Antibody Analytics we can provide real time readouts of all of our cytotoxicity-based assays including ADCC, CDC, T cell mediated cytotoxicity and exhausted T cell formats.
Novocyte Quanteon
Antibody Analytics understands the importance and power of in-depth cell analysis for biopharmaceutical development. The Quanteon system is a 4-laser flow cytometer that can be configured with up to 25 independent photomultipliers, giving us and our customers the freedom to push our assay design further than imagined.
The Novocyte Quanteon is used to provide beautiful data in many of our assay formats, such as cytotoxicity, proliferation and activation.
Luminex Magpix
Employing MAGPIX-based cytokine analysis not only maximises the amount of cytokine production data that can be gleaned from a single experimental set up, it can yield the discovery of cytokine changes that may not have been anticipated. Providing you with more insight on your molecule’s mode of action. The panel can be tailored to suit your needs, be it an off-the-shelf panel or bespoke, Antibody Analytics will work with you to ensure the panel answers your scientific questions.
Are you interested in determining the quantities of multiple cytokines in a single sample? Perhaps you’re unsure of the secondary effects of your therapeutic and want to screen for unknown alterations in a wider cytokine panel? This is where MAGPIX offers several advantages over conventional ELISA approaches, with up to 50 analytes measurable per sample.
Cell Line Development
Antibody Analytics offers custom cell line development services to support bioassay development. Using our proprietary CHO Luc cells for viability and cytotoxicity assays, we have been able to support a wide range of common and less common targets. With an extensive library already available and future targets already identified, Antibody Analytics can undertake bespoke customer projects in the event commercially available cell line solutions are inappropriate.
All cell line development projects are carried out in a data driven manner. Custom cell lines can be created for biological characterisation in early discovery, through to lot release.
Antibody Analytics Ltd.
Antibody Analytics wins Innovate UK SMART award
Antibody Analytics wins Innovate UK SMART award and begins work on transformational cell platform, IndEx-2 Antibody Analytics are pleased to announce that they have been awarded a coveted and highly competitive SMART grant from Innovate UK, the UK's innovation...
Ways to check your set up is correct
You've spent all of your lab time making the perfect SPR assay. Your data looks great, the Sensorgrams overlay like they are a single curve and then the inevitable happens; someone asks: "How do you know it's reliable?" Assessing the fit First thing to do is look at...
Control Your Variables
No matter what type of experiment you embark on, controlling your variables is vital to understanding whether your assay is behaving properly, and the output is reliable and actionable. To avoid writing a novel on this topic, I have tried to streamline my thoughts on...
What’s your Question?
What's your question? To avoid wasting time and money, it is critical you start with the end in mind, and spend time clearly deciding what question you're looking for an answer to. Do you want to know the kinetics of a single interaction or against a large panel of...
Effector cell considerations
The population of effector cells used in cell-based cytotoxicity assays such as TMC is an important consideration. Depending on how sensitive or therapeutically relevant your assay needs to be will dictate what sort of effector preparation should be used. The more...
Key Materials And Reagents
One of the easiest ways to make beautiful assays is to ensure that you have effectively considered what sensor chips, buffers and other reagents are right for the job. Choosing your sensor chip An important part of setting up an assay is to ensure that the correct...
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